Increased expression of androgen receptor (AR) in prostate cancer (PC) is associated with transition to androgen independence.Because the progression of PC to advanced stages is often associated with the loss of p53 function, we tested whether the p53 could regulate the expression of AR gene.Here we report that p53 negatively regulates the expressi
ABSTRACT Notwithstanding the importance of soil surveys, advances in digital soil mapping have mainly focused on mapping soil attributes or properties rather than developing digital maps of soil units or soil classes.The purpose of this research was to develop digital soil unit maps based on primary soil data collection in areas without previously
In the 1970s a new musical genre called rap appeared in the United States, continuing the tradition of rock Tanning Foam and punk music.In about twenty years, this new form of protest poetry created global sociolinguistic changes because its presence helped shape a special social group with a special lexicon and grammar.Rap uses both standard and c
A hybrid charge pump was developed in a 0.13- $mu ext{m}$ Bipolar-CMOS-DMOS (BCD) process which utilised high drain-source voltage MOS devices and low-voltage integrated metal-insulator-metal (MIM) capacitors.The design consisted of a zero-reversion loss cross-coupled stage and a new self-biased serial-parallel charge pump design.The latter has be
Deodorante Fournier gangrene (FG) is polymicrobial necrotizing infection of subcutaneous tissues and deep fascia, commonly involving the perineum, external genitalia, anterior abdominal wall and medial aspect of thighs.Urethral pathology, although often the inciting factor for FG, extensive involvement with urethral necrosis is very rare.This is th